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Urethral obstruction may cause excessive bladder distension resulting in detrusor atony or weakness, which disrupts tight junctions between muscle cells. This is common in cats with。

Severe bladetrusor atony catdder distension, which often results in detrusor atony and inability to void; Grossly abnormal urine or cystic calculi, both of which increase the risk for immediate recurrent UO. ... urination within 72 hours, occurred in 11 of 15。

If reflex of the detrusor exists and but it is insufficient to induce a suitable evacuation, it is possible to stimulate the contraction of the bladder using some Prokinetics as the Cisapride (dogs 0.1-0.5 mg/kg c/8-12 hrs. and cats 2.5-5 mg。

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